POINT PREVALENCE OF COLORECTAL CANCER IN A MEGA CITY OF PAKISTAN, KARACHI – A CROSS SECTIONAL STUDY

Background and Objective: Globally, Colorectal Cancers are also third most common cancers fourth leading cause of death due to carcinoma. Burden is high in Pakistan. The main risk factor for Cancer age, however, other factors e.g. family history, irritable bowel disease, sedentary life-style, visceral adipose tissues, smoking alcohol. Hence; the objective current study was determine point prevalence a mega city Pakistan, Karachi; representative population It hypothesized that incidences would be higher Karachi than rest country. Materials Methods: retrospective cross-sectional conducted Karachi. Duration from January-2015 October-2019. Data has been collected two state-owned four private hospitals Precision analysis technique used sample size study. Study approved by Board Advanced Studies & Research, University (Reference Number: BASR/01046/Pharm.). Objective explained patients before initiation study; informed consent taken each patient. S.P.S.S (Statistical-Package-for-Social-Sciences) software version 22 analyze data. Results: Among 1,617 patients: male 54.35% (N=879); female 45.64% (N=738). Mean age diagnosis colorectal cancer: 49.51±14.72 years; 45.28±13.52 years. Significantly found ethnicity speaking Sindhi compared with Balochi (p=0.001), Pashto (p=0.0001), Punjabi (p=0.001) Siraiki (p=0.0001); Urdu (p=0.0001) male. In female; significantly (p=0.028); (p=0.012), (p=0.002), (p=0.002) (p=0.0001). Conclusion: Allocation resources required at governmental non-governmental level early screening. National cancer registry program should initiated support health policy makers development counter strategies. Peer Review History: Received: 26 February 2023; Revised: 13 March; Accepted: 27 April 2023, Available online: 15 May 2023 Academic Editor: Prof. Cyprian Ogbonna ONYEJI, Obafemi Awolowo University, Ile-Ife, Nigeria, [email protected] Received file: Reviewer's Comments: Average review marks initial stage: 5.5/10 publication 7.0/10 Reviewers: Dr. Bilge Ahsen KARA, Ankara Gazi Mustafa Kemal Hospital, Turkey, [email protected] A.A. Mgbahurike, Port Harcourt, [email protected]